Sung-Chyr Lin, Professor & Chairman

	Tel:886-4-22852587; 886-4-22840510 ext 512

	E-mail: sclin@nchu.edu.tw

Ph.D. in Chemical Engineering, University of Texas at Austin (1993)

Research Interests

Dr. Lin’s laboratory is currently involved in researches in the fields of enzyme technology, protein engineering, protein purification, and applied genetic engineering. In the filed of enzyme technology, Dr. Lin, in conjunction with colleagues in the Institute of Molecular biology, focuses on the development of novel enzymatic processes of production of chiral compounds for the synthesis of pharmaceutics. In the fields of protein engineering and protein purification, he is particular interested in developing novel processes for protein refolding from inclusion bodies and protein purification. In light of the significance of bacterial systems for the production of recombinant proteins, Dr. Lin is aiming at developing improved E. coli systems for protein expression via genetic engineering. 　

Selected Publications

  A Biocatalyst for the Removal of Sulfite from Alcoholic Beverages. (with Georgiou), Biotechnology and Bioengineering, in press.

  Purification of Recombinant Proteins with Hydroxyapatite -based Immobilized Metal Affinity Adsorbents. (with Suen and Hsu), Journal of Chromatography, 2004.

  Integrated Enzyme Purification and Immobilization Processes with Immobilized Metal Affinity Adsorbents. (with Ho, Lee and Hsu), Process Biochemistry, 2004.

  Temperature-responsive polymer-assisted protein refolding. (Chen, Huang and Chiu), Enzyme and Microbial Technology, 2003.

  Anchorage of Cyclodextrin Glucanotransferase on the Outer Membrane of Escherichia coli. (with Wan and Chang), Biotechnology and Bioengineering, 2002.

Enhanced protein renaturation by temperature-responsive polymers. (with Lin, Lin and Chiu), Biotechnology and Bioengineering, 2000.

 Production of D-amino acid precursors with permeabilized recombinant Escherichia coli with D-hydantoinase activity. (with Ying, Chen     and   Hsu), Process Biochemistry, 2000.